Gustavo Restrepo lectures in architecture at both UPB and Santo Tomas University, and has lectured at various colleges and symposiums of architecture, urbanism and new materials in Central and South America.

He studied architecture and planning at UPB (1990) and also obtained a Masters in Engineering New Materials from UPB (2005).

Gustavo Restrepo worked for the Urban Development Corporation (EDU), where he was responsible for realizing the development plan (2008-11) of the Mayor of Medellín for security and living, health, education, and public spaces.

He is a consultant in the areas of architectural design and planning, design, and construction management. Public and private sector clients include regional television channel Teleantioquia, and the Cultural Civic Center Plaza Botero: Museum of Antioquia. He was director of the Biennale Medellin MDE 11 and is an assessor for the Medellín city development plan.

Gustavo Restrepo won the Holcim Awards Gold 2008 Latin America for Urban integration of an informal area, Medellín, Colombia after winning a Holcim Awards Encouragement prize 2005 Latin America for the project From temporary shelters to permanent housing, Medellín, Colombia.