Loreta co-founded Taller Capital with José Ambrosi in 2010. The architecture and urban design firm mainly focuses on the design of housing and infrastructural public spaces to fix the broken city. Their work has been subject to several national and international recognitions such as the MCHAP.emerge from Chicago IIT, the Architectural League of NY Emerging Architects and the Iberoamerican Architecture Biennial.

Loreta teaches at Estudio RX in the School of Architecture at Universidad Nacional Autónoma de México (UNAM) and has been visiting professor at several universities in Latin America, Europe and the USA. She has been interviewed by the New York Times and El País, and has written several essays for different publications worldwide.

She joined the Board of the Holcim Foundation for Sustainable Construction in November 2023. 

She studied architecture at UNAM graduating with Suma Cum Laude (2004). She holds a Master of Architecture from the Accademia di Architettura di Mendrisio (AAM) in Switzerland (2004), where Peter Zumthor was her tutor for two years. She also holds a Master of Architecture in Urban Design with Distinction from the Harvard Graduate School of Design (2010).

As a result of focusing her research on water and city design, she received the 2010 Druker Traveling Fellowship awarded by Harvard GSD. She was the design director and technical coordinator of the UNAM project Hydropuncture in Mexico City, which received the Global Holcim Awards Gold 2018 and Holcim Awards Gold 2017 for region Latin America. The project was praised by the jury for “foregrounding an extremely important challenge for contemporary and future society”.

Loreta Castro Reguera was head of the Holcim Awards jury for region Latin America in 2020. She was a Motivator at the Holcim Next Generation Awards Lab 2018 held in Mexico City and a workshop presenter on Shifting the flows, pulling the strings: Stocks, flows, and their dynamics at the 6th International Holcim Forum for Sustainable Construction in Cairo, April 4-6, 2019.